Medications for Short-Course Chemotherapy of Drug Resistant Tuberculosis and Their Effect on the Host
نویسندگان
چکیده
The review presents up-to-date data from 88 publications devoted to the short-course regimens of multiple drug resistant tuberculosis treatment and describes characteristics most effective drugs – bedaquiline, linezolid, delamanid, clofazimine. Information is also provided on additional properties drugs, i.e. modulation key immune response immunometabolic processes that underlie a new approach improvement treatment, so-called host therapy.
منابع مشابه
Short-course chemotherapy for tuberculosis.
Although short-course, largely twice weekly chemotherapy for treatment of tuberculosis has been shown to be effective in other countries, when given under closely controlled conditions, it has not been adopted in this country where most patients are older and are treated as outpatients. Since January, 1976, 315 patients (mean age 55.5 years) with proven pulmonary tuberculosis have been treated ...
متن کاملThe effect of initial drug resistance on treatment response and acquired drug resistance during standardized short-course chemotherapy for tuberculosis.
BACKGROUND In Tomsk Oblast, Russian Federation, during the period of 1996-2000, most previously untreated patients with tuberculosis received standardized short-course chemotherapy, irrespective of drug-susceptibility testing results. A retrospective analysis was done to determine the effect of initial drug resistance on treatment outcome and acquired drug resistance in new patients receiving s...
متن کاملStandard short-course chemotherapy for drug-resistant tuberculosis: treatment outcomes in 6 countries.
CONTEXT No large-scale study has investigated the impact of multidrug-resistant tuberculosis (TB) on the outcome of standard short-course chemotherapy under routine countrywide TB control program conditions in the World Health Organization's (WHO) directly observed treatment short-course strategy for TB control. OBJECTIVE To assess the results of treatment with first-line drugs for patients e...
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ژورنال
عنوان ژورنال: ?????????? ? ??????? ??????
سال: 2022
ISSN: ['2542-1506', '2075-1230']
DOI: https://doi.org/10.21292/2075-1230-2022-100-8-54-64